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Xencor Initiates Phase 1 Study of XmAb7195 for Asthma (Xencor Inc)

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(Source: Xencor Inc) MONROVIA, Calif., May 28, 2014 /PRNewswire/ -- Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases, and cancer, today announced that the first subject has been dosed in a Phase 1a clinical trial of XmAb®7195. XmAb7195 is a monoclonal antibody engineered to suppress IgE via three distinct mechanisms of action as a potential treatment for asthma and other atopic disease. "XmAb7195 achieved very low levels of serum IgE in preclinical studies and offers the potential for superior IgE control," said Bassil Dahiyat, Ph.D.,...

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